Publications

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Journal Article
Brigham, C. J., Speth, D. R., Rha, C. K. & Sinskey, A. J. Whole-genome microarray and gene deletion studies reveal regulation of the polyhydroxyalkanoate production cycle by the stringent response in Ralstonia eutropha H16. Appl Environ Microbiol 78, 8033-44 (2012).
Budde, C. F., Mahan, A. E., Lu, J., Rha, C. K. & Sinskey, A. J. Roles of multiple acetoacetyl coenzyme A reductases in polyhydroxybutyrate biosynthesis in Ralstonia eutropha H16. J Bacteriol 192, 5319-28 (2010).
Kurosawa, K. et al. Rhodostreptomycins, antibiotics biosynthesized following horizontal gene transfer from Streptomyces padanus to Rhodococcus fascians. J Am Chem Soc 130, 1126-7 (2008).
Riedel, S. L. et al. Recovery of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from Ralstonia eutropha cultures with non-halogenated solvents. Biotechnol Bioeng 110, 461-70 (2013).
Budde, C. F., Riedel, S. L., Willis, L. B., Rha, C. K. & Sinskey, A. J. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. Appl Environ Microbiol 77, 2847-54 (2011).
Riedel, S. L. et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by Ralstonia eutropha in high cell density palm oil fermentations. Biotechnol Bioeng 109, 74-83 (2012).
Sambanthamurthi, R. et al. Positive outcomes of oil palm phenolics on degenerative diseases in animal models. Br J Nutr 106, 1664-75 (2011).
Yang, Y. - H. et al. Optimization of growth media components for polyhydroxyalkanoate (PHA) production from organic acids by Ralstonia eutropha. Appl Microbiol Biotechnol 87, 2037-45 (2010).
Sambanthamurthi, R. et al. Oil palm vegetation liquor: a new source of phenolic bioactives. Br J Nutr 106, 1655-63 (2011).
Weinberg, R. P. et al. Oil Palm Phenolics Inhibit the Aggregation of -Amyloid Peptide into Oligomeric Complexes. Int J Alzheimers Dis 2018, 7608038 (2018).
Lawrence, A. G., Choi, J., Rha, C. K., Stubbe, J. & Sinskey, A. J. In vitro analysis of the chain termination reaction in the synthesis of poly-(R)-beta-hydroxybutyrate by the class III synthase from Allochromatium vinosum. Biomacromolecules 6, 2113-9 (2005).
Yang, Y. - H., Brigham, C., Willis, L., Rha, C. K. & Sinskey, A. Improved detergent-based recovery of polyhydroxyalkanoates (PHAs). Biotechnol Lett 33, 937-42 (2011).
Budde, C. F. et al. Growth and polyhydroxybutyrate production by Ralstonia eutropha in emulsified plant oil medium. Appl Microbiol Biotechnol 89, 1611-9 (2011).
Osman, A. et al. Genetic diversity of Eurycoma longifolia inferred from single nucleotide polymorphisms. Plant Physiol 131, 1294-301 (2003).
Coldren, C. D. et al. Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids. Planta Med 69, 725-32 (2003).
Brigham, C. J., Reimer, E. N., Rha, C. K. & Sinskey, A. J. Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis. AMB Express 2, 26 (2012).
Brigham, C. J. et al. Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression. J Bacteriol 192, 5454-64 (2010).
Brigham, C. J., Speth, D. R., Rha, C. K. & Sinskey, A. J. Correction for Brigham et al., "Whole-Genome Microarray and Gene Deletion Studies Reveal Regulation of the Polyhydroxyalkanoate Production Cycle by the Stringent Response in Ralstonia eutropha H16". Appl Environ Microbiol 83, (2017).
Bhubalan, K. et al. Characterization of the highly active polyhydroxyalkanoate synthase of Chromobacterium sp. strain USM2. Appl Environ Microbiol 77, 2926-33 (2011).
Lu, J., Brigham, C. J., Rha, C. K. & Sinskey, A. J. Characterization of an extracellular lipase and its chaperone from Ralstonia eutropha H16. Appl Microbiol Biotechnol 97, 2443-54 (2013).
Jeon, J. - M. et al. Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(HB-co-HHx)) from butyrate using engineered Ralstonia eutropha. Appl Microbiol Biotechnol 98, 5461-9 (2014).
Wong, Y. - M., Brigham, C. J., Rha, C. K., Sinskey, A. J. & Sudesh, K. Biosynthesis and characterization of polyhydroxyalkanoate containing high 3-hydroxyhexanoate monomer fraction from crude palm kernel oil by recombinant Cupriavidus necator. Bioresour Technol 121, 320-7 (2012).
Gorret, N. et al. Bioreactor culture of oil palm (Elaeis guineensis) and effects of nitrogen source, inoculum size, and conditioned medium on biomass production. J Biotechnol 108, 253-63 (2004).
Rafat, M. et al. Association (micellization) and partitioning of aglycon triterpenoids. J Colloid Interface Sci 325, 324-30 (2008).
Miyasaka, Y., Rha, C. K. & Sinskey, A. J. Application of temperature-sensitive mutants for single-cell protein production. Biotechnol Bioeng 22, 2065-2079 (1980).