Publications

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2016
Plassmeier, J., Li, Y., Rueckert, C. & Sinskey, A. J. Metabolic engineering Corynebacterium glutamicum to produce triacylglycerols. Metab Eng 33, 86-97 (2016).
2013
Murueva, A. V., Shishatskaya, E. I., Kuzmina, A. M., Volova, T. G. & Sinskey, A. J. Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug. J Mater Sci Mater Med 24, 1905-15 (2013).
Fuchs, B. C. et al. Molecular MRI of collagen to diagnose and stage liver fibrosis. J Hepatol 59, 992-8 (2013).
2012
Brigham, C. J., Zhila, N., Shishatskaya, E., Volova, T. G. & Sinskey, A. J. Manipulation of Ralstonia eutropha carbon storage pathways to produce useful bio-based products. Subcell Biochem 64, 343-66 (2012).
2011
Lee, K. S., Boccazzi, P., Sinskey, A. J. & Ram, R. J. Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture. Lab Chip 11, 1730-9 (2011).
2006
Lee, H. L. T., Boccazzi, P., Ram, R. J. & Sinskey, A. J. Microbioreactor arrays with integrated mixers and fluid injectors for high-throughput experimentation with pH and dissolved oxygen control. Lab Chip 6, 1229-35 (2006).
Zhang, Z. et al. Microchemostat-microbial continuous culture in a polymer-based, instrumented microbioreactor. Lab Chip 6, 906-13 (2006).
2004
Zanzotto, A. et al. Membrane-aerated microbioreactor for high-throughput bioprocessing. Biotechnol Bioeng 87, 243-54 (2004).
2002
Lessard, P. A., Kulaveerasingam, H., York, G. M., Strong, A. & Sinskey, A. J. Manipulating gene expression for the metabolic engineering of plants. Metab Eng 4, 67-79 (2002).
2001
Jia, Y. et al. Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism. Biochemistry 40, 1011-9 (2001).
Guillouet, S. et al. Metabolic redirection of carbon flow toward isoleucine by expressing a catabolic threonine dehydratase in a threonine-overproducing Corynebacterium glutamicum. Appl Microbiol Biotechnol 57, 667-73 (2001).
1999
Park, S. M., Klapa, M. I., Sinskey, A. J. & Stephanopoulos, G. Metabolite and isotopomer balancing in the analysis of metabolic cycles: II. Applications. Biotechnol Bioeng 62, 392-401 (1999).
Klapa, M. I., Park, S. M., Sinskey, A. J. & Stephanopoulos, G. Metabolite and isotopomer balancing in the analysis of metabolic cycles: I. Theory. Biotechnol Bioeng 62, 375-391 (1999).
1997
Park, S. M., Sinskey, A. J. & Stephanopoulos, G. Metabolic and physiological studies of Corynebacterium glutamicum mutants. Biotechnol Bioeng 55, 864-79 (1997).
1996
Shelikoff, M., Sinskey, A. J. & Stephanopoulos, G. A modeling framework for the study of protein glycosylation. Biotechnol Bioeng 50, 73-90 (1996).
1995
Hwang, C., Lodish, H. F. & Sinskey, A. J. Measurement of glutathione redox state in cytosol and secretory pathway of cultured cells. Methods Enzymol 251, 212-21 (1995).
1994
Jetten, M. S., Follettie, M. T. & Sinskey, A. J. Metabolic engineering of Corynebacterium glutamicum. Ann N Y Acad Sci 721, 12-29 (1994).
1993
Stephanopoulos, G. & Sinskey, A. J. Metabolic engineering--methodologies and future prospects. Trends Biotechnol 11, 392-6 (1993).
1990
von der Osten, C. H. et al. Molecular cloning of aldolases for synthetic applications. Ann N Y Acad Sci 613, 771-5 (1990).
Han, K. S., Archer, J. A. & Sinskey, A. J. The molecular structure of the Corynebacterium glutamicum threonine synthase gene. Mol Microbiol 4, 1693-702 (1990).
1989
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: II. The relationship between thiol chemistry and the degradation of serum activity. Biotechnol Bioeng 33, 440-50 (1989).
Thompson, S. et al. Mechanistic studies on beta-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes. Biochemistry 28, 5735-42 (1989).
von der Osten, C. H., Barbas, C. F., Wong, C. H. & Sinskey, A. J. Molecular cloning, nucleotide sequence and fine-structural analysis of the Corynebacterium glutamicum fda gene: structural comparison of C. glutamicum fructose-1,6-biphosphate aldolase to class I and class II aldolases. Mol Microbiol 3, 1625-37 (1989).
1988
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: I. Initial metabolic rates. Biotechnol Bioeng 32, 491-506 (1988).
1986
Follettie, M. T. & Sinskey, A. J. Molecular cloning and nucleotide sequence of the Corynebacterium glutamicum pheA gene. J Bacteriol 167, 695-702 (1986).
Jamas, S., Rha, C. & Sinskey, A. J. Morphology of yeast cell wall as affected by genetic manipulation of beta(1 --> 6) glycosidic linkage. Biotechnol Bioeng 28, 769-84 (1986).
1977
Montville, T. J., Cooney, C. L. & Sinskey, A. J. Measurement and synthesis of insoluble and soluble dextran by Streptococcus mutans. J Dent Res 56, 983-9 (1977).
1973
Gomez, R. F., Sinskey, A. J., Davies, R. & Labuza, T. P. Minimal medium recovery of heated Salmonella typhimurium LT2. J Gen Microbiol 74, 267-74 (1973).
1970
Morhart, R. E., Mata, L. J., Sinskey, A. J. & Harris, R. S. A microbiological and biochemical study of gingival crevice debris obtained from Guatemalan Mayan Indians. J Periodontol 41, 644-9 (1970).