Publications

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G
Gerngross, T. U. et al. Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 33, 9311-20 (1994).
Gerngross, T. U., Reilly, P., Stubbe, J., Sinskey, A. J. & Peoples, O. P. Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. J Bacteriol 175, 5289-93 (1993).
Giard, D. J., Fleischaker, R. J. & Sinskey, A. J. Kinetics of human beta interferon production under different temperature conditions. J Interferon Res 2, 471-7 (1982).
Glacken, M. W., Fleischaker, R. J. & Sinskey, A. J. Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up. Ann N Y Acad Sci 413, 355-72 (1983).
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: I. Initial metabolic rates. Biotechnol Bioeng 32, 491-506 (1988).
Glacken, M. W., Fleischaker, R. J. & Sinskey, A. J. Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells. Biotechnol Bioeng 28, 1376-89 (1986).
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: II. The relationship between thiol chemistry and the degradation of serum activity. Biotechnol Bioeng 33, 440-50 (1989).
Glanemann, C. et al. Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysis. Appl Microbiol Biotechnol 61, 61-8 (2003).
Gomez, R. F. & Sinskey, A. J. Effect of aeration on minimal medium recovery of heated Salmonella typhimurium. J Bacteriol 122, 106-9 (1975).
Gomez, R. F. & Sinskey, A. J. DNA breaks in rifampin-treated Salmonella typhimurium LT2 after exposure to nutritionally complex media. Nature 247, 211-2 (1974).
Gomez, R. F., Johnston, M. & Sinskey, A. J. Activation of nitrosomorpholine and nitrosopyrrolidine to bacterial mutagens. Mutat Res 24, 5-7 (1974).
Gomez, R. F., Sinskey, A. J., Davies, R. & Labuza, T. P. Minimal medium recovery of heated Salmonella typhimurium LT2. J Gen Microbiol 74, 267-74 (1973).
Gomez, R. F., Blais, K. D., Herrero, A. & Sinskey, A. J. Effects of inhibitors of protein, RNA and DNA synthesis on heat-injured Salmonella typhimurium LT2. J Gen Microbiol 97, 19-27 (1976).
Gomez, R., Takano, M. & Sinskey, A. J. Proceedings: Characteristics of freeze-dried cells. Cryobiology 10, 368-74 (1973).
Gomez, R. F. & Sinskey, A. J. Deoxyribonucleic acid breaks in heated Salmonella typhimurium LT-2 after exposure to nutritionally complex media. J Bacteriol 115, 522-8 (1973).
Gorret, N. et al. Bioreactor culture of oil palm (Elaeis guineensis) and effects of nitrogen source, inoculum size, and conditioned medium on biomass production. J Biotechnol 108, 253-63 (2004).
Goswami, J., Sinskey, A. J., Steller, H., Stephanopoulos, G. N. & Wang, D. I. Apoptosis in batch cultures of Chinese hamster ovary cells. Biotechnol Bioeng 62, 632-40 (1999).
Govindan, G. et al. A bioactive polyacetylene compound isolated from Centella asiatica. Planta Med 73, 597-9 (2007).
Grousseau, E., Lu, J., Gorret, N., Guillouet, S. E. & Sinskey, A. J. Isopropanol production with engineered Cupriavidus necator as bioproduction platform. Appl Microbiol Biotechnol 98, 4277-90 (2014).
Grunwald, S. et al. Kinetic and stoichiometric characterization of organoautotrophic growth of Ralstonia eutropha on formic acid in fed-batch and continuous cultures. Microb Biotechnol 8, 155-63 (2015).
Gubler, M., Jetten, M., Lee, S. H. & Sinskey, A. J. Cloning of the pyruvate kinase gene (pyk) of Corynebacterium glutamicum and site-specific inactivation of pyk in a lysine-producing Corynebacterium lactofermentum strain. Appl Environ Microbiol 60, 2494-500 (1994).
Guillouet, S., Rodal, A. A., An, G., Lessard, P. A. & Sinskey, A. J. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 65, 3100-7 (1999).
Guillouet, S. et al. Metabolic redirection of carbon flow toward isoleucine by expressing a catabolic threonine dehydratase in a threonine-overproducing Corynebacterium glutamicum. Appl Microbiol Biotechnol 57, 667-73 (2001).
H
Han, K. S., Archer, J. A. & Sinskey, A. J. The molecular structure of the Corynebacterium glutamicum threonine synthase gene. Mol Microbiol 4, 1693-702 (1990).
Holder, J. W. et al. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. PLoS Genet 7, e1002219 (2011).
Hwang, C., Lodish, H. F. & Sinskey, A. J. Measurement of glutathione redox state in cytosol and secretory pathway of cultured cells. Methods Enzymol 251, 212-21 (1995).
Hwang, C., Sinskey, A. J. & Lodish, H. F. Oxidized redox state of glutathione in the endoplasmic reticulum. Science 257, 1496-502 (1992).
I
Ibe, S. N., Sinskey, A. J. & Botstein, D. Genetic mapping of mutations in a highly radiation-resistant mutant of Salmonella typhimurium LT2. J Bacteriol 152, 260-8 (1982).
Imada, A., Hunt, J. W., Van De Sande, H., Sinskey, A. J. & Tannenbaum, S. R. Puridication and properties of an intracellular ribonuclease from Candida lipolytica. Biochim Biophys Acta 395, 490-500 (1975).
Imada, A., Sinskey, A. J. & Tannenbaum, S. R. A new macromolecular inhibitor of yeast ribonuclease mediated through purine nucleotides. Biochim Biophys Acta 268, 674-9 (1972).
Imada, A., Sinskey, A. J. & Tannenbaum, S. R. Degradation of ribonucleic acid in Candida lipolytica: extraction of ribonucleic acid degrading enzymes. Biotechnol Bioeng 14, 103-22 (1972).
J
Jain, J., Valge-Archer, V. E., Sinskey, A. J. & Rao, A. The AP-1 site at -150 bp, but not the NF-kappa B site, is likely to represent the major target of protein kinase C in the interleukin 2 promoter. J Exp Med 175, 853-62 (1992).
Jamas, S., Rha, C. & Sinskey, A. J. Morphology of yeast cell wall as affected by genetic manipulation of beta(1 --> 6) glycosidic linkage. Biotechnol Bioeng 28, 769-84 (1986).
Jeon, J. - M. et al. Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(HB-co-HHx)) from butyrate using engineered Ralstonia eutropha. Appl Microbiol Biotechnol 98, 5461-9 (2014).
Jetten, M. S. & Sinskey, A. J. Recent advances in the physiology and genetics of amino acid-producing bacteria. Crit Rev Biotechnol 15, 73-103 (1995).
Jetten, M. S., Follettie, M. T. & Sinskey, A. J. Metabolic engineering of Corynebacterium glutamicum. Ann N Y Acad Sci 721, 12-29 (1994).
Jetten, M. S. & Sinskey, A. J. Purification and properties of oxaloacetate decarboxylase from Corynebacterium glutamicum. Antonie Van Leeuwenhoek 67, 221-7 (1995).
Jetten, M. S., Gubler, M. E., Lee, S. H. & Sinskey, A. J. Structural and functional analysis of pyruvate kinase from Corynebacterium glutamicum. Appl Environ Microbiol 60, 2501-7 (1994).
Jetten, M. S., Follettie, M. T. & Sinskey, A. J. Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum. Appl Microbiol Biotechnol 43, 76-82 (1995).
Jia, Y., Kappock, T. J., Frick, T., Sinskey, A. J. & Stubbe, J. Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: characterization of the functional residues in Chromatium vinosum PHB synthase. Biochemistry 39, 3927-36 (2000).
Jia, Y. et al. Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism. Biochemistry 40, 1011-9 (2001).
Juengert, J. R. et al. Absence of ppGpp Leads to Increased Mobilization of Intermediately Accumulated Poly(3-Hydroxybutyrate) in Ralstonia eutropha H16. Appl Environ Microbiol 83, (2017).
K
Kimble, C. E., Gorczyca, P. A. & Sinskey, A. J. Repair of lesions induced in human liver cell DNA by N-nitroso compounds as measured by the bromodeoxyuridine photolysis method. Mutat Res 24, 35-9 (1974).
Klapa, M. I., Park, S. M., Sinskey, A. J. & Stephanopoulos, G. Metabolite and isotopomer balancing in the analysis of metabolic cycles: I. Theory. Biotechnol Bioeng 62, 375-391 (1999).
Knorr, D. & Sinskey, A. J. Biotechnology in food production and processing. Science 229, 1224-9 (1985).
Koffas, M. A., Ramamoorthi, R., Pine, W. A., Sinskey, A. J. & Stephanopoulos, G. Sequence of the Corynebacterium glutamicum pyruvate carboxylase gene. Appl Microbiol Biotechnol 50, 346-52 (1998).
Kurosawa, K., Radek, A., Plassmeier, J. K. & Sinskey, A. J. Improved glycerol utilization by a triacylglycerol-producing Rhodococcus opacus strain for renewable fuels. Biotechnol Biofuels 8, 31 (2015).
Kurosawa, K., MacEachran, D. P. & Sinskey, A. J. Antibiotic biosynthesis following horizontal gene transfer: new milestone for novel natural product discovery?. Expert Opin Drug Discov 5, 819-25 (2010).
Kurosawa, K., Plassmeier, J., Kalinowski, J., Rückert, C. & Sinskey, A. J. Engineering L-arabinose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production. Metab Eng 30, 89-95 (2015).
Kurosawa, K., Boccazzi, P., de Almeida, N. M. & Sinskey, A. J. High-cell-density batch fermentation of Rhodococcus opacus PD630 using a high glucose concentration for triacylglycerol production. J Biotechnol 147, 212-8 (2010).

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