Publications

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D
Loos, A. et al. Development and validation of corynebacterium DNA microarrays. Appl Environ Microbiol 67, 2310-8 (2001).
Szita, N. et al. Development of a multiplexed microbioreactor system for high-throughput bioprocessing. Lab Chip 5, 819-26 (2005).
Boccazzi, P. et al. Differential gene expression profiles and real-time measurements of growth parameters in Saccharomyces cerevisiae grown in microliter-scale bioreactors equipped with internal stirring. Biotechnol Prog 22, 710-7 (2006).
Batt, C. A., Caryallo, S., Easson, D. D., Akedo, M. & Sinskey, A. J. Direct evidence for a xylose metabolic pathway in Saccharomyces cerevisiae. Biotechnol Bioeng 28, 549-53 (1986).
Glanemann, C. et al. Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysis. Appl Microbiol Biotechnol 61, 61-8 (2003).
Montville, T. J., Cooney, C. L. & Sinskey, A. J. Distribution of dextransucrase in Streptococcus mutans and observations on the effect of soluble dextran on dextransucrase activities. Infect Immun 18, 629-35 (1977).
Gomez, R. F. & Sinskey, A. J. DNA breaks in rifampin-treated Salmonella typhimurium LT2 after exposure to nutritionally complex media. Nature 247, 211-2 (1974).
Archer, J. A. & Sinskey, A. J. The DNA sequence and minimal replicon of the Corynebacterium glutamicum plasmid pSR1: evidence of a common ancestry with plasmids from C. diphtheriae. J Gen Microbiol 139, 1753-9 (1993).
E
Gomez, R. F. & Sinskey, A. J. Effect of aeration on minimal medium recovery of heated Salmonella typhimurium. J Bacteriol 122, 106-9 (1975).
Awerbuch, T. E. & Sinskey, A. J. The effect of different genetic properties of Salmonella typhimurium on the determination of stabilities and mutagenic concentrations of chemical carcinogens using the diffusion bioassay. Mutat Res 113, 13-9 (1983).
Jetten, M. S., Follettie, M. T. & Sinskey, A. J. Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum. Appl Microbiol Biotechnol 43, 76-82 (1995).
Colón, G. E. et al. Effect of inducible thrB expression on amino acid production in Corynebacterium lactofermentum ATCC 21799. Appl Environ Microbiol 61, 74-8 (1995).
Shelikoff, M., Sinskey, A. J. & Stephanopoulos, G. The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin. Cytotechnology 15, 195-208 (1994).
Augenstein, D. C., Sinskey, A. J. & Wang, D. I. Effect of shear on the death of two strains of mammalian tissue cells. Biotechnol Bioeng 13, 409-18 (1971).
Gomez, R. F., Blais, K. D., Herrero, A. & Sinskey, A. J. Effects of inhibitors of protein, RNA and DNA synthesis on heat-injured Salmonella typhimurium LT2. J Gen Microbiol 97, 19-27 (1976).
Volova, T. G., Zhila, N. O., Kalacheva, G. S., Brigham, C. J. & Sinskey, A. J. Effects of intracellular poly(3-hydroxybutyrate) reserves on physiological-biochemical properties and growth of Ralstonia eutropha. Res Microbiol 164, 164-71 (2013).
Brigham, C. J. et al. Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression. J Bacteriol 192, 5454-64 (2010).
Song, Y. et al. Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production. Appl Microbiol Biotechnol 93, 1917-25 (2012).
O'Brien, X. M., Parker, J. A., Lessard, P. A. & Sinskey, A. J. Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons. Appl Microbiol Biotechnol 59, 389-99 (2002).
Kurosawa, K., Plassmeier, J., Kalinowski, J., Rückert, C. & Sinskey, A. J. Engineering L-arabinose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production. Metab Eng 30, 89-95 (2015).
Kurosawa, K., Wewetzer, S. J. & Sinskey, A. J. Engineering xylose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production. Biotechnol Biofuels 6, 134 (2013).
Brigham, C. J., Reimer, E. N., Rha, C. K. & Sinskey, A. J. Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis. AMB Express 2, 26 (2012).
Bernardi, A. C., Gai, C. S., Lu, J., Sinskey, A. J. & Brigham, C. J. Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha. J Biosci Bioeng 122, 64-9 (2016).
Guillouet, S., Rodal, A. A., An, G., Lessard, P. A. & Sinskey, A. J. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 65, 3100-7 (1999).
Liebl, W., Sinskey, A. J. & Schleifer, K. H. Expression, secretion, and processing of staphylococcal nuclease by Corynebacterium glutamicum. J Bacteriol 174, 1854-61 (1992).
Chung, J. D., Zabel, C., Sinskey, A. J. & Stephanopoulos, G. Extension of Sp2/0 hybridoma cell viability through interleukin-6 supplementation. Biotechnol Bioeng 55, 439-46 (1997).
F
Peoples, O. P. & Sinskey, A. J. Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding beta-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB. Mol Microbiol 3, 349-57 (1989).
Shaw-Reid, C. A., McCormick, M. M., Sinskey, A. J. & Stephanopoulos, G. Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum. Appl Microbiol Biotechnol 51, 325-33 (1999).
Stallings, S. C. et al. A framework to evaluate the economic impact of pharmacogenomics. Pharmacogenomics 7, 853-62 (2006).
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Boccazzi, P. et al. Gene expression analysis of Escherichia coli grown in miniaturized bioreactor platforms for high-throughput analysis of growth and genomic data. Appl Microbiol Biotechnol 68, 518-32 (2005).
Coldren, C. D. et al. Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids. Planta Med 69, 725-32 (2003).
Follettie, M. T., Peoples, O. P., Agoropoulou, C. & Sinskey, A. J. Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon. J Bacteriol 175, 4096-103 (1993).
Yeh, P., Sicard, A. M. & Sinskey, A. J. General organization of the genes specifically involved in the diaminopimelate-lysine biosynthetic pathway of Corynebacterium glutamicum. Mol Gen Genet 212, 105-11 (1988).
Osman, A. et al. Genetic diversity of Eurycoma longifolia inferred from single nucleotide polymorphisms. Plant Physiol 131, 1294-301 (2003).
Pellon, J. R. & Sinskey, A. J. Genetic engineering for food and additives. Soc Appl Bacteriol Symp Ser 11, 287-300 (1983).
Ibe, S. N., Sinskey, A. J. & Botstein, D. Genetic mapping of mutations in a highly radiation-resistant mutant of Salmonella typhimurium LT2. J Bacteriol 152, 260-8 (1982).
Cho, C. W. et al. Glioblastoma cell death induced by asiatic acid. Cell Biol Toxicol 22, 393-408 (2006).
Budde, C. F. et al. Growth and polyhydroxybutyrate production by Ralstonia eutropha in emulsified plant oil medium. Appl Microbiol Biotechnol 89, 1611-9 (2011).
Chung, J. D., Sinskey, A. J. & Stephanopoulos, G. Growth factor and bcl-2 mediated survival during abortive proliferation of hybridoma cell line. Biotechnol Bioeng 57, 164-71 (1998).
H
Pellon, J. R. & Sinskey, A. J. Heat-induced damage to the bacterial chromosome and its repair. Soc Appl Bacteriol Symp Ser 105-25 (1984).
Kurosawa, K., Boccazzi, P., de Almeida, N. M. & Sinskey, A. J. High-cell-density batch fermentation of Rhodococcus opacus PD630 using a high glucose concentration for triacylglycerol production. J Biotechnol 147, 212-8 (2010).
I
Gerngross, T. U., Reilly, P., Stubbe, J., Sinskey, A. J. & Peoples, O. P. Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. J Bacteriol 175, 5289-93 (1993).
Yang, Y. - H., Brigham, C., Willis, L., Rha, C. K. & Sinskey, A. Improved detergent-based recovery of polyhydroxyalkanoates (PHAs). Biotechnol Lett 33, 937-42 (2011).
Kurosawa, K., Radek, A., Plassmeier, J. K. & Sinskey, A. J. Improved glycerol utilization by a triacylglycerol-producing Rhodococcus opacus strain for renewable fuels. Biotechnol Biofuels 8, 31 (2015).
Zanzotto, A. et al. In situ measurement of bioluminescence and fluorescence in an integrated microbioreactor. Biotechnol Bioeng 93, 40-7 (2006).
Lawrence, A. G., Choi, J., Rha, C. K., Stubbe, J. & Sinskey, A. J. In vitro analysis of the chain termination reaction in the synthesis of poly-(R)-beta-hydroxybutyrate by the class III synthase from Allochromatium vinosum. Biomacromolecules 6, 2113-9 (2005).
White, G. E., Cooney, C. L., Sinskey, A. J. & Miller, S. A. An in vitro assay to measure early calcium loss from surface enamel. J Dent Res 53, 481-5 (1974).
Priefert, H. et al. Indene bioconversion by a toluene inducible dioxygenase of Rhodococcus sp. I24. Appl Microbiol Biotechnol 65, 168-76 (2004).
Gai, C. S., Lu, J., Brigham, C. J., Bernardi, A. C. & Sinskey, A. J. Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16. AMB Express 4, 2 (2014).
Fleischaker, R. J., Weaver, J. C. & Sinskey, A. J. Instrumentation for process control in cell culture. Adv Appl Microbiol 27, 137-67 (1981).

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