Publications

Export 215 results:
Author Title [ Type(Asc)] Year
Journal Article
Lessard, P. A., Kulaveerasingam, H., York, G. M., Strong, A. & Sinskey, A. J. Manipulating gene expression for the metabolic engineering of plants. Metab Eng 4, 67-79 (2002).
Jia, Y., Kappock, T. J., Frick, T., Sinskey, A. J. & Stubbe, J. Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: characterization of the functional residues in Chromatium vinosum PHB synthase. Biochemistry 39, 3927-36 (2000).
Kurosawa, K., C Debono, A. & Sinskey, A. J. Lignocellulose-derived inhibitors improve lipid extraction from wet Rhodococcus opacus cells. Bioresour Technol 193, 206-12 (2015).
Stewart, S. R. et al. Leveraging Industry-Academia Collaborations in Adaptive Biomedical Innovation. Clin Pharmacol Ther 100, 647-653 (2016).
Glacken, M. W., Fleischaker, R. J. & Sinskey, A. J. Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up. Ann N Y Acad Sci 413, 355-72 (1983).
Pellon, J. R., Sinskey, A. J., Hecht, S. M. & Gomez, R. F. Kinetics of the bleomycin A2 damage in vivo to the folded chromosome of Escherichia coli. Chem Biol Interact 43, 245-51 (1983).
Giard, D. J., Fleischaker, R. J. & Sinskey, A. J. Kinetics of human beta interferon production under different temperature conditions. J Interferon Res 2, 471-7 (1982).
Tian, J., Sinskey, A. J. & Stubbe, J. Kinetic studies of polyhydroxybutyrate granule formation in Wautersia eutropha H16 by transmission electron microscopy. J Bacteriol 187, 3814-24 (2005).
Grunwald, S. et al. Kinetic and stoichiometric characterization of organoautotrophic growth of Ralstonia eutropha on formic acid in fed-batch and continuous cultures. Microb Biotechnol 8, 155-63 (2015).
Grousseau, E., Lu, J., Gorret, N., Guillouet, S. E. & Sinskey, A. J. Isopropanol production with engineered Cupriavidus necator as bioproduction platform. Appl Microbiol Biotechnol 98, 4277-90 (2014).
Easson, D. D., Sinskey, A. J. & Peoples, O. P. Isolation of Zoogloea ramigera I-16-M exopolysaccharide biosynthetic genes and evidence for instability within this region. J Bacteriol 169, 4518-24 (1987).
Treadway, S. L. et al. Isolation and characterization of indene bioconversion genes from Rhodococcus strain I24. Appl Microbiol Biotechnol 51, 786-93 (1999).
Ulmer, K. M., Gomez, R. F. & Sinskey, A. J. Ionizing radiation damage to the folded chromosome of Escherichia coli K-12: repair of double-strand breaks in deoxyribonucleic acid. J Bacteriol 138, 486-91 (1979).
Ulmer, K. M., Gomez, R. F. & Sinskey, A. J. Ionizing radiation damage to the folded chromosome of Escherichia coli K-12: sedimentation properties of irradiated nucleoids and chromosomal deoxyribonucleic acid. J Bacteriol 138, 475-85 (1979).
Zupke, C., Sinskey, A. J. & Stephanopoulos, G. Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol 44, 27-36 (1995).
Fleischaker, R. J., Weaver, J. C. & Sinskey, A. J. Instrumentation for process control in cell culture. Adv Appl Microbiol 27, 137-67 (1981).
Gai, C. S., Lu, J., Brigham, C. J., Bernardi, A. C. & Sinskey, A. J. Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16. AMB Express 4, 2 (2014).
Priefert, H. et al. Indene bioconversion by a toluene inducible dioxygenase of Rhodococcus sp. I24. Appl Microbiol Biotechnol 65, 168-76 (2004).
White, G. E., Cooney, C. L., Sinskey, A. J. & Miller, S. A. An in vitro assay to measure early calcium loss from surface enamel. J Dent Res 53, 481-5 (1974).
Lawrence, A. G., Choi, J., Rha, C. K., Stubbe, J. & Sinskey, A. J. In vitro analysis of the chain termination reaction in the synthesis of poly-(R)-beta-hydroxybutyrate by the class III synthase from Allochromatium vinosum. Biomacromolecules 6, 2113-9 (2005).
Zanzotto, A. et al. In situ measurement of bioluminescence and fluorescence in an integrated microbioreactor. Biotechnol Bioeng 93, 40-7 (2006).
Kurosawa, K., Radek, A., Plassmeier, J. K. & Sinskey, A. J. Improved glycerol utilization by a triacylglycerol-producing Rhodococcus opacus strain for renewable fuels. Biotechnol Biofuels 8, 31 (2015).
Yang, Y. - H., Brigham, C., Willis, L., Rha, C. K. & Sinskey, A. Improved detergent-based recovery of polyhydroxyalkanoates (PHAs). Biotechnol Lett 33, 937-42 (2011).
Gerngross, T. U., Reilly, P., Stubbe, J., Sinskey, A. J. & Peoples, O. P. Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. J Bacteriol 175, 5289-93 (1993).
Kurosawa, K., Boccazzi, P., de Almeida, N. M. & Sinskey, A. J. High-cell-density batch fermentation of Rhodococcus opacus PD630 using a high glucose concentration for triacylglycerol production. J Biotechnol 147, 212-8 (2010).
Pellon, J. R. & Sinskey, A. J. Heat-induced damage to the bacterial chromosome and its repair. Soc Appl Bacteriol Symp Ser 105-25 (1984).
Chung, J. D., Sinskey, A. J. & Stephanopoulos, G. Growth factor and bcl-2 mediated survival during abortive proliferation of hybridoma cell line. Biotechnol Bioeng 57, 164-71 (1998).
Budde, C. F. et al. Growth and polyhydroxybutyrate production by Ralstonia eutropha in emulsified plant oil medium. Appl Microbiol Biotechnol 89, 1611-9 (2011).
Cho, C. W. et al. Glioblastoma cell death induced by asiatic acid. Cell Biol Toxicol 22, 393-408 (2006).
Ibe, S. N., Sinskey, A. J. & Botstein, D. Genetic mapping of mutations in a highly radiation-resistant mutant of Salmonella typhimurium LT2. J Bacteriol 152, 260-8 (1982).
Pellon, J. R. & Sinskey, A. J. Genetic engineering for food and additives. Soc Appl Bacteriol Symp Ser 11, 287-300 (1983).
Osman, A. et al. Genetic diversity of Eurycoma longifolia inferred from single nucleotide polymorphisms. Plant Physiol 131, 1294-301 (2003).
Yeh, P., Sicard, A. M. & Sinskey, A. J. General organization of the genes specifically involved in the diaminopimelate-lysine biosynthetic pathway of Corynebacterium glutamicum. Mol Gen Genet 212, 105-11 (1988).
Follettie, M. T., Peoples, O. P., Agoropoulou, C. & Sinskey, A. J. Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon. J Bacteriol 175, 4096-103 (1993).
Coldren, C. D. et al. Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids. Planta Med 69, 725-32 (2003).
Boccazzi, P. et al. Gene expression analysis of Escherichia coli grown in miniaturized bioreactor platforms for high-throughput analysis of growth and genomic data. Appl Microbiol Biotechnol 68, 518-32 (2005).
Stallings, S. C. et al. A framework to evaluate the economic impact of pharmacogenomics. Pharmacogenomics 7, 853-62 (2006).
Shaw-Reid, C. A., McCormick, M. M., Sinskey, A. J. & Stephanopoulos, G. Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum. Appl Microbiol Biotechnol 51, 325-33 (1999).
Peoples, O. P. & Sinskey, A. J. Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding beta-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB. Mol Microbiol 3, 349-57 (1989).
Chung, J. D., Zabel, C., Sinskey, A. J. & Stephanopoulos, G. Extension of Sp2/0 hybridoma cell viability through interleukin-6 supplementation. Biotechnol Bioeng 55, 439-46 (1997).
Liebl, W., Sinskey, A. J. & Schleifer, K. H. Expression, secretion, and processing of staphylococcal nuclease by Corynebacterium glutamicum. J Bacteriol 174, 1854-61 (1992).
Guillouet, S., Rodal, A. A., An, G., Lessard, P. A. & Sinskey, A. J. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 65, 3100-7 (1999).
Bernardi, A. C., Gai, C. S., Lu, J., Sinskey, A. J. & Brigham, C. J. Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha. J Biosci Bioeng 122, 64-9 (2016).
Brigham, C. J., Reimer, E. N., Rha, C. K. & Sinskey, A. J. Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis. AMB Express 2, 26 (2012).
Kurosawa, K., Wewetzer, S. J. & Sinskey, A. J. Engineering xylose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production. Biotechnol Biofuels 6, 134 (2013).
Kurosawa, K., Plassmeier, J., Kalinowski, J., Rückert, C. & Sinskey, A. J. Engineering L-arabinose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production. Metab Eng 30, 89-95 (2015).
O'Brien, X. M., Parker, J. A., Lessard, P. A. & Sinskey, A. J. Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons. Appl Microbiol Biotechnol 59, 389-99 (2002).
Song, Y. et al. Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production. Appl Microbiol Biotechnol 93, 1917-25 (2012).
Brigham, C. J. et al. Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression. J Bacteriol 192, 5454-64 (2010).
Volova, T. G., Zhila, N. O., Kalacheva, G. S., Brigham, C. J. & Sinskey, A. J. Effects of intracellular poly(3-hydroxybutyrate) reserves on physiological-biochemical properties and growth of Ralstonia eutropha. Res Microbiol 164, 164-71 (2013).

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