Publications

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G
Gomez, R. F., Sinskey, A. J., Davies, R. & Labuza, T. P. Minimal medium recovery of heated Salmonella typhimurium LT2. J Gen Microbiol 74, 267-74 (1973).
Gomez, R. F., Blais, K. D., Herrero, A. & Sinskey, A. J. Effects of inhibitors of protein, RNA and DNA synthesis on heat-injured Salmonella typhimurium LT2. J Gen Microbiol 97, 19-27 (1976).
Gomez, R., Takano, M. & Sinskey, A. J. Proceedings: Characteristics of freeze-dried cells. Cryobiology 10, 368-74 (1973).
Gomez, R. F. & Sinskey, A. J. Deoxyribonucleic acid breaks in heated Salmonella typhimurium LT-2 after exposure to nutritionally complex media. J Bacteriol 115, 522-8 (1973).
Gomez, R. F. & Sinskey, A. J. Effect of aeration on minimal medium recovery of heated Salmonella typhimurium. J Bacteriol 122, 106-9 (1975).
Gomez, R. F. & Sinskey, A. J. DNA breaks in rifampin-treated Salmonella typhimurium LT2 after exposure to nutritionally complex media. Nature 247, 211-2 (1974).
Gomez, R. F., Johnston, M. & Sinskey, A. J. Activation of nitrosomorpholine and nitrosopyrrolidine to bacterial mutagens. Mutat Res 24, 5-7 (1974).
Glanemann, C. et al. Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysis. Appl Microbiol Biotechnol 61, 61-8 (2003).
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: I. Initial metabolic rates. Biotechnol Bioeng 32, 491-506 (1988).
Glacken, M. W., Fleischaker, R. J. & Sinskey, A. J. Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells. Biotechnol Bioeng 28, 1376-89 (1986).
Glacken, M. W., Adema, E. & Sinskey, A. J. Mathematical descriptions of hybridoma culture kinetics: II. The relationship between thiol chemistry and the degradation of serum activity. Biotechnol Bioeng 33, 440-50 (1989).
Glacken, M. W., Fleischaker, R. J. & Sinskey, A. J. Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up. Ann N Y Acad Sci 413, 355-72 (1983).
Giard, D. J., Fleischaker, R. J. & Sinskey, A. J. Kinetics of human beta interferon production under different temperature conditions. J Interferon Res 2, 471-7 (1982).
Gerngross, T. U. et al. Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 33, 9311-20 (1994).
Gerngross, T. U., Reilly, P., Stubbe, J., Sinskey, A. J. & Peoples, O. P. Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. J Bacteriol 175, 5289-93 (1993).
Gai, C. S., Lu, J., Brigham, C. J., Bernardi, A. C. & Sinskey, A. J. Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16. AMB Express 4, 2 (2014).
C
Colón, G. E. et al. Effect of inducible thrB expression on amino acid production in Corynebacterium lactofermentum ATCC 21799. Appl Environ Microbiol 61, 74-8 (1995).
Colón, G. E., Nguyen, T. T., Jetten, M. S., Sinskey, A. J. & Stephanopoulos, G. Production of isoleucine by overexpression of ilvA in a Corynebacterium lactofermentum threonine producer. Appl Microbiol Biotechnol 43, 482-8 (1995).
Coldren, C. D. et al. Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids. Planta Med 69, 725-32 (2003).
Chung, J. D., Zabel, C., Sinskey, A. J. & Stephanopoulos, G. Extension of Sp2/0 hybridoma cell viability through interleukin-6 supplementation. Biotechnol Bioeng 55, 439-46 (1997).
Chung, J. D., Sinskey, A. J. & Stephanopoulos, G. Growth factor and bcl-2 mediated survival during abortive proliferation of hybridoma cell line. Biotechnol Bioeng 57, 164-71 (1998).
Chow, J. J., Batt, C. A. & Sinskey, A. J. Characterization of Lactobacillus bulgaricus Bacteriophage ch2. Appl Environ Microbiol 54, 1138-42 (1988).
Cho, C. W. et al. Glioblastoma cell death induced by asiatic acid. Cell Biol Toxicol 22, 393-408 (2006).
Cho, M., Brigham, C. J., Sinskey, A. J. & Stubbe, J. Purification of polyhydroxybutyrate synthase from its native organism, Ralstonia eutropha: implications for the initiation and elongation of polymer formation in vivo. Biochemistry 51, 2276-88 (2012).
Chen, K., Stephanopoulos, G. N., Sinskey, A. J. & Lodish, H. F. Regulated secretion of prolactin by the mouse insulinoma cell line beta TC-3. Biotechnology (N Y) 13, 1191-7 (1995).
Castro, A. C., Sinskey, A. J. & Tannenbaum, S. R. Reduction of nucleic acid content in Candida yeast cells by bovine pancreatic ribonuclease A treatment. Appl Microbiol 22, 422-7 (1971).
Cao, J. et al. Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production. ACS Synth Biol 7, 896-902 (2018).
B
Butterworth, T. A., Wang, D. I. & Sinskey, A. J. Application of ultrafiltration for enzyme retention during continuous enzymatic reaction. Biotechnol Bioeng 12, 615-31 (1970).
Budde, C. F. et al. Growth and polyhydroxybutyrate production by Ralstonia eutropha in emulsified plant oil medium. Appl Microbiol Biotechnol 89, 1611-9 (2011).
Budde, C. F., Riedel, S. L., Willis, L. B., Rha, C. K. & Sinskey, A. J. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. Appl Environ Microbiol 77, 2847-54 (2011).
Budde, C. F., Mahan, A. E., Lu, J., Rha, C. K. & Sinskey, A. J. Roles of multiple acetoacetyl coenzyme A reductases in polyhydroxybutyrate biosynthesis in Ralstonia eutropha H16. J Bacteriol 192, 5319-28 (2010).
Brigham, C. J., Speth, D. R., Rha, C. K. & Sinskey, A. J. Whole-genome microarray and gene deletion studies reveal regulation of the polyhydroxyalkanoate production cycle by the stringent response in Ralstonia eutropha H16. Appl Environ Microbiol 78, 8033-44 (2012).
Brigham, C. J. et al. Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression. J Bacteriol 192, 5454-64 (2010).
Brigham, C. J., Zhila, N., Shishatskaya, E., Volova, T. G. & Sinskey, A. J. Manipulation of Ralstonia eutropha carbon storage pathways to produce useful bio-based products. Subcell Biochem 64, 343-66 (2012).
Brigham, C. J., Reimer, E. N., Rha, C. K. & Sinskey, A. J. Examination of PHB Depolymerases in Ralstonia eutropha: Further Elucidation of the Roles of Enzymes in PHB Homeostasis. AMB Express 2, 26 (2012).
Brigham, C. J., Speth, D. R., Rha, C. K. & Sinskey, A. J. Correction for Brigham et al., "Whole-Genome Microarray and Gene Deletion Studies Reveal Regulation of the Polyhydroxyalkanoate Production Cycle by the Stringent Response in Ralstonia eutropha H16". Appl Environ Microbiol 83, (2017).
Boudrant, J., DeAngelo, J., Sinskey, A. J. & Tannenbaum, S. R. Process characteristics of cell lysis mutants of Saccharomyces cerevisiae. Biotechnol Bioeng 21, 659-70 (1979).
Bor, Y. C. et al. Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase. Gene 114, 127-32 (1992).

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