Publications

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2018
Ranganathan, B., Miller, C. & Sinskey, A. Biocompatible Synthetic and Semi-synthetic Polymers - A Patent Analysis. Pharm Nanotechnol 6, 28-37 (2018).
2017
Juengert, J. R. et al. Absence of ppGpp Leads to Increased Mobilization of Intermediately Accumulated Poly(3-Hydroxybutyrate) in Ralstonia eutropha H16. Appl Environ Microbiol 83, (2017).
Marc, J. et al. Over expression of GroESL in Cupriavidus necator for heterotrophic and autotrophic isopropanol production. Metab Eng 42, 74-84 (2017).
2015
Grunwald, S. et al. Kinetic and stoichiometric characterization of organoautotrophic growth of Ralstonia eutropha on formic acid in fed-batch and continuous cultures. Microb Biotechnol 8, 155-63 (2015).
2013
Murueva, A. V., Shishatskaya, E. I., Kuzmina, A. M., Volova, T. G. & Sinskey, A. J. Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug. J Mater Sci Mater Med 24, 1905-15 (2013).
MacEachran, D. P. & Sinskey, A. J. The Rhodococcus opacus TadD protein mediates triacylglycerol metabolism by regulating intracellular NAD(P)H pools. Microb Cell Fact 12, 104 (2013).
2012
Song, Y. et al. Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production. Appl Microbiol Biotechnol 93, 1917-25 (2012).
2010
Kurosawa, K., MacEachran, D. P. & Sinskey, A. J. Antibiotic biosynthesis following horizontal gene transfer: new milestone for novel natural product discovery?. Expert Opin Drug Discov 5, 819-25 (2010).
Brigham, C. J. et al. Elucidation of beta-oxidation pathways in Ralstonia eutropha H16 by examination of global gene expression. J Bacteriol 192, 5454-64 (2010).
MacEachran, D. P., Prophete, M. E. & Sinskey, A. J. The Rhodococcus opacus PD630 heparin-binding hemagglutinin homolog TadA mediates lipid body formation. Appl Environ Microbiol 76, 7217-25 (2010).
Budde, C. F., Mahan, A. E., Lu, J., Rha, C. K. & Sinskey, A. J. Roles of multiple acetoacetyl coenzyme A reductases in polyhydroxybutyrate biosynthesis in Ralstonia eutropha H16. J Bacteriol 192, 5319-28 (2010).
2006
Stallings, S. C. et al. A framework to evaluate the economic impact of pharmacogenomics. Pharmacogenomics 7, 853-62 (2006).
2004
Ozminkowski, R. J. et al. The use of disease-modifying new drugs for multiple sclerosis treatment in private-sector health plans. Clin Ther 26, 1341-54 (2004).
2003
Osman, A. et al. Genetic diversity of Eurycoma longifolia inferred from single nucleotide polymorphisms. Plant Physiol 131, 1294-301 (2003).
Nielsen, U. B., Cardone, M. H., Sinskey, A. J., MacBeath, G. & Sorger, P. K. Profiling receptor tyrosine kinase activation by using Ab microarrays. Proc Natl Acad Sci U S A 100, 9330-5 (2003).
2001
Yuan, W. et al. Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and Allochromatium vinosum: characterization and substrate specificity studies. Arch Biochem Biophys 394, 87-98 (2001).
1999
Shaw-Reid, C. A., McCormick, M. M., Sinskey, A. J. & Stephanopoulos, G. Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum. Appl Microbiol Biotechnol 51, 325-33 (1999).
Müh, U., Sinskey, A. J., Kirby, D. P., Lane, W. S. & Stubbe, J. PHA synthase from chromatium vinosum: cysteine 149 is involved in covalent catalysis. Biochemistry 38, 826-37 (1999).
1994
Gerngross, T. U. et al. Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 33, 9311-20 (1994).
1992
Williams, S. F. et al. Biosynthetic thiolase from Zoogloea ramigera. Mutagenesis of the putative active-site base Cys-378 to Ser-378 changes the partitioning of the acetyl S-enzyme intermediate. J Biol Chem 267, 16041-3 (1992).
Bor, Y. C. et al. Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase. Gene 114, 127-32 (1992).
1991
Palmer, M. A. et al. Biosynthetic thiolase from Zoogloea ramigera. Evidence for a mechanism involving Cys-378 as the active site base. J Biol Chem 266, 8369-75 (1991).
1990
Marcel, T., Archer, J. A., Mengin-Lecreulx, D. & Sinskey, A. J. Nucleotide sequence and organization of the upstream region of the Corynebacterium glutamicum lysA gene. Mol Microbiol 4, 1819-30 (1990).
Marcel, T., Archer, J. A., Mengin-Lecreulx, D. & Sinskey, A. J. Nucleotide sequence and organization of the upstream region of the Corynebacterium glutamicum lysA gene. Mol Microbiol 4, 1819-30 (1990).
1989
Thompson, S. et al. Mechanistic studies on beta-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes. Biochemistry 28, 5735-42 (1989).
Thompson, S. et al. Mechanistic studies on beta-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes. Biochemistry 28, 5735-42 (1989).
1988
Peoples, O. P. et al. Nucleotide sequence and fine structural analysis of the Corynebacterium glutamicum hom-thrB operon. Mol Microbiol 2, 63-72 (1988).
1987
Davis, J. T. et al. Biosynthetic thiolase from zoogloea ramigera. I. Preliminary characterization and analysis of proton transfer reaction. J Biol Chem 262, 82-9 (1987).
Davis, J. T. et al. Biosynthetic thiolase from zoogloea ramigera. I. Preliminary characterization and analysis of proton transfer reaction. J Biol Chem 262, 82-9 (1987).
Davis, J. T. et al. Biosynthetic thiolase from Zoogloea ramigera. II. Inactivation with haloacetyl CoA analogs. J Biol Chem 262, 90-6 (1987).
Davis, J. T. et al. Biosynthetic thiolase from Zoogloea ramigera. II. Inactivation with haloacetyl CoA analogs. J Biol Chem 262, 90-6 (1987).
Peoples, O. P., Masamune, S., Walsh, C. T. & Sinskey, A. J. Biosynthetic thiolase from Zoogloea ramigera. III. Isolation and characterization of the structural gene. J Biol Chem 262, 97-102 (1987).
1980
Miyasaka, Y., Rha, C. K. & Sinskey, A. J. Application of temperature-sensitive mutants for single-cell protein production. Biotechnol Bioeng 22, 2065-2079 (1980).
1979
Lee, C. H., Montville, T. J. & Sinskey, A. J. Comparison of the efficacy of steam sterilization indicators. Appl Environ Microbiol 37, 1113-7 (1979).
1978
Montville, T. J., Cooney, C. L. & Sinskey, A. J. Streptococcus mutans dextransucrase: a review. Adv Appl Microbiol 24, 55-84 (1978).
1977
Montville, T. J., Cooney, C. L. & Sinskey, A. J. Distribution of dextransucrase in Streptococcus mutans and observations on the effect of soluble dextran on dextransucrase activities. Infect Immun 18, 629-35 (1977).
Montville, T. J., Cooney, C. L. & Sinskey, A. J. Measurement and synthesis of insoluble and soluble dextran by Streptococcus mutans. J Dent Res 56, 983-9 (1977).
1976
White, G. E., Cooney, G. L., Sinskey, A. J. & Miller, S. A. Continuous culture studies on the growth and physiology of Streptococcus mutans. J Dent Res 55, 239-43 (1976).
1974
White, G. E., Cooney, C. L., Sinskey, A. J. & Miller, S. A. An in vitro assay to measure early calcium loss from surface enamel. J Dent Res 53, 481-5 (1974).
1971
Ohta, S., Maul, S., Sinskey, A. J. & Tannenbaum, S. R. Characterization of a heat-shock process for reduction of the nucleic acid content of Candida utilis. Appl Microbiol 22, 415-21 (1971).
1970
Morhart, R. E., Mata, L. J., Sinskey, A. J. & Harris, R. S. A microbiological and biochemical study of gingival crevice debris obtained from Guatemalan Mayan Indians. J Periodontol 41, 644-9 (1970).
Morhart, R. E., Mata, L. J., Sinskey, A. J. & Harris, R. S. A microbiological and biochemical study of gingival crevice debris obtained from Guatemalan Mayan Indians. J Periodontol 41, 644-9 (1970).
Maul, S. B., Sinskey, A. J. & Tannenbaum, S. R. New process for reducing the nucleic acid content of yeast. Nature 228, 181 (1970).